LONG-TERM SEDATIVE USE – EFFECTS, RISKS & PREVENTATIVE MEASURES

2. Histamine Receptor Antagonism: Some sedatives, including antihistamines, exert their sedative effects by blocking histamine receptors in the brain, especially H1 receptors. Histamine plays a role in wakefulness and arousal, so blocking its effects encourages sedation and sleepiness.Addiction can be a brain problem. Don’t experience like there�